Chronic kidney disease affects more than 10% of the worldwide population. Approximately 25% of those individuals with chronic kidney disease can identify a family history of chronic kidney disease. Chronic kidney disease stage 1, 2, and 3 can often be asymptomatic and go undetected until stage 4 or 5, advanced stage kidney disease. At stage 4 or 5 chronic kidney disease, the traditional approach of diagnosis with a renal biopsy may be unrevealing or even contraindicated. Thus, in 10% of adult cases of newly diagnosed end stage kidney disease the clinical diagnosis is said to be "unknown."
There has been recent evidence to suggest that a genetic cause of kidney disease can be detected in one in every ten individuals with chronic kidney disease. Genetic testing can help identify certain individuals at risk for rapid progression and can assist in targeting appropriate therapy. Genetic testing is now more accessible to the chronic kidney disease population when obtained under the guidance of a Nephrologist in the appropriate circumstance. Early detection and accurate diagnosis of chronic kidney disease can be very important in guiding therapy to delay progression of chronic kidney disease and can even help identify other family members who may be affected.
If you are interested in learning more about genetic testing which can be performed at our clinic, please call 817-233-6923 to schedule a consultation.